1． Group members:
Ø Rongtao Li: Professor (group leader)
Ø Haizhou Li: Associate Professor
Ø Xiaolei Li: Lecturer
Ø Hongmei Li: Lecturer
Ø Linghuan Gao: Lecturer
Ø Dan Liu: Lecturer
Natural medicinal chemistry and modernization of traditional Chinese medicine research group is a young group which was interested in the structure, function and the relationship between structure and function of bioactive compounds from natural medicine and Chinese traditional medicine. We are focusing on the extraction, isolation, structural elucidation and bioactivity test of the natural bioactive compounds.
There are six members in this group. As a group leader, Professor Rongtao Li has received the following awards: the “National Excellent Doctoral Dissertation of P.R. China”, the “New Century Excellent Talents on University”, the “Young Academic and Technical Leader of Yunnan Province”, the “Excellent Scholar of Fok Ying Tong”, the “Excellent Doctoral Dissertation of the Chinese Academy of Science”, and “CPA-Servier Yong Investigator Awards in Medicinal Chemistry”.
A set of instruments for the investigation of natural Chinese medicine bioactive compounds are available in our group, such as Agilent 1200 high performance liquid chromatography, Büchi medium pressure liquid chromatography (MPLC), rotary evaporator, low temperature coolant circulation pump, etc. In addition, cell culture room is under construction.
The main focus of our current research is the phytochemistry, physiological activity and biopharmaceutical aspects of traditionally used medicinal plants and their constituents.
(1) Comprehensive research on the active constituents of traditionally used herbals, their isolation by bio-guided fractionation, and their identification is necessary to get insight into their chemistry, biological activity (pharmacology and toxicology), and synergistic properties.
(2) Identification of novel natural products with inflammatory, immunomodulatory and anti-virus effects.
(3) The chemical constituents, bioactivity and poisonous mechanism of Yunnan toxin plant and their application in medicine.
Now our group is undertaking several foundation items, involving the investigation of chemical constituents of several Chinese Medicinal plant, as well as their bioactivities. So far the group members have published 132 academic papers, of which 91 are SCI (38 articles above SCI impact factor 3.0). 16 patents wereappliedrelating to Professor Li’s discovery and 6 have already been authorized.
The group is responsible for the curriculums of Natural medicinal chemistry, Physiology, Spectroscopic methods of organic compound (bilingualism), the Principle of medicinal chemistry and Pharmaceutical botany for undergraduates, as well as the courses of Advanced organic chemistry,Structure analysis of organic compounds and Advanced drug chemistry for master degree candidates.
Until now, the research group has trained more than 30 undergraduate students and 15 masters, and now the group has 25 graduate students and 6 Ph.D candidates.
We would like to organize and participate in a wide range of domestic and international academic exchange activities, which helps the group follow the newest research progress in the field.
Prospective master and bachelor students who are interested in natural medicine chemistry research are welcome to join our group!